Understanding the result
This result should be interpreted with symptoms, medical history and other investigations. An abnormal value does not identify the cause by itself.
About CA-125 — Ovarian Cancer Marker
This specialized tumor marker test measures the concentration of Cancer Antigen 125 (CA-125) protein in the blood. CA-125 is a surface antigen primarily shed by ovarian cancer cells, making it a key biomarker for evaluating ovarian health and cellular abnormalities. Why it is important: The CA-125 test is a crucial clinical tool used primarily for monitoring therapeutic responses during ovarian cancer treatment and detecting early signs of disease recurrence. While it is not a definitive standalone screening tool for the general population—as benign conditions like pelvic inflammatory disease, endometriosis, or menstruation can also cause elevated levels—it provides vital diagnostic insights when evaluated alongside clinical imaging for high-risk individuals.
Also known as: Cancer Antigen 125, Ovarian Cancer Marker Test, CA-125 Blood Test, Tumor Marker CA-125, CA125 Glycoprotein Test
Who may need it?
A healthcare professional may recommend this test based on your symptoms, medical history, risk factors or need for routine monitoring.
What is the CA-125 Ovarian Cancer Marker Test?
The CA-125 (Cancer Antigen 125) blood test is a specialized diagnostic tool primarily used as a cancer screening and monitoring aid. CA-125 is a protein found in high concentrations on the surface of ovarian cancer cells. It is shed into the bloodstream, making it a valuable biomarker for detecting potential cellular abnormalities and assessing ovarian health.
What Does This Test Measure?
This test measures the exact concentration of the CA-125 glycoprotein in your blood plasma:
- CA-125 Levels: Elevated levels of this protein are frequently associated with ovarian cancer cells. However, slight elevations can also occur due to benign conditions such as pregnancy, menstruation, endometriosis, or pelvic inflammatory disease (PID).
Why is the CA-125 Test Important?
While not used exclusively as a standalone diagnostic tool for everyone, the CA-125 profile is incredibly important for several clinical reasons:
- Monitoring Treatment: For individuals undergoing therapy for ovarian cancer, tracking CA-125 levels helps oncologists determine if the treatment (such as chemotherapy or surgery) is successfully reducing the cancer load.
- Detecting Recurrence: It serves as an early warning system to monitor for the return or recurrence of ovarian cancer after treatment completion.
- High-Risk Evaluation: It provides critical diagnostic insights when evaluated alongside imaging tests (like ultrasounds) for women presenting with a pelvic mass or those with a strong family history of ovarian cancer.
Parameters included
Frequently Asked Questions
What does the CA-125 — Ovarian Cancer Marker test measure? +
The CA-125 — Ovarian Cancer Marker measures: CA-125.
Is fasting required for CA-125 — Ovarian Cancer Marker? +
No fasting is required.
How much does CA-125 — Ovarian Cancer Marker cost in Vadodara? +
The CA-125 — Ovarian Cancer Marker costs ₹1395 in Vadodara. Home sample collection is included.
When will I get my CA-125 — Ovarian Cancer Marker results? +
Provider report guidance: 24 hours. Reports are delivered digitally when ready.
Is home sample collection available in Vadodara? +
Home sample collection is available in supported Vadodara localities. It is included for this test.